Research fields

The fields of aging science covered by the directory. Each links to its leading people and organisations.

1. Cellular senescence 25 people · 13 labs
2. Senolytics & senomorphics 7 people · 5 labs
3. Stem cell biology 25 people · 10 labs
4. iPSC reprogramming 6 people · 3 labs
5. Partial epigenetic reprogramming 7 people · 5 labs
6. Epigenetic aging clocks 4 people · 5 labs
7. Proteomic / metabolomic / transcriptomic clocks 1 people · 2 labs
8. Telomeres & telomerase 7 people · 4 labs
9. Mitochondrial dysfunction 21 people · 8 labs
10. Mitophagy & mitochondrial QC 8 people · 1 labs
11. Proteostasis & autophagy 17 people · 7 labs
12. Chaperone-mediated autophagy 1 people · 1 labs
13. Ubiquitin–proteasome system 1 people · 0 labs
14. Genomic instability & DNA repair 14 people · 5 labs
15. Nutrient sensing & mTOR 12 people · 7 labs
16. AMPK & sirtuins 14 people · 4 labs
17. Insulin / IGF-1 signalling 7 people · 3 labs
18. Caloric-restriction mimetics 6 people · 1 labs
19. Fasting & fasting-mimicking 6 people · 3 labs
20. Rapalogs 9 people · 6 labs
21. Metformin geroscience 3 people · 1 labs
22. GLP-1 & incretins in aging 2 people · 3 labs
23. Inflammation & inflammaging 17 people · 8 labs
24. NLRP3 inflammasome 2 people · 3 labs
25. Immunosenescence 5 people · 3 labs
26. Thymus & immune rejuvenation 2 people · 0 labs
27. Intercellular communication & exosomes 1 people · 0 labs
28. Extracellular matrix & fibrosis 7 people · 6 labs
29. Proteoglycans, crosslinks & glucosepane 2 people · 1 labs
30. Amyloid & extracellular aggregates 2 people · 4 labs
31. NAD+ metabolism 8 people · 1 labs
32. One-carbon metabolism & methylation 3 people · 1 labs
33. Lipids, Lp(a) & atherosclerosis in aging 0 people · 1 labs
34. Cardiovascular aging 1 people · 0 labs
35. Neuroinflammation 2 people · 1 labs
36. Brain aging & cognition 9 people · 2 labs
37. Parkinson's & aging overlap 4 people · 1 labs
38. Alzheimer's geroscience 21 people · 7 labs
39. Sarcopenia & muscle 2 people · 0 labs
40. Bone & osteoporosis in aging 2 people · 1 labs
41. Reproductive & ovarian aging 0 people · 2 labs
42. Skin & ocular aging 0 people · 2 labs
43. Kidney aging 0 people · 1 labs
44. Pulmonary aging & IPF 4 people · 4 labs
45. Cancer–aging interface 1 people · 0 labs
46. Comparative biology of long-lived species 4 people · 2 labs
47. Naked mole-rat & exceptional longevity 3 people · 2 labs
48. Centenarian genetics 9 people · 2 labs
49. Human genetic longevity variants 0 people · 2 labs
50. Parabiosis & plasma factors 6 people · 1 labs
51. Young-blood factors & GDF11 debate 2 people · 0 labs
52. Microbiome & aging 5 people · 1 labs
53. Circadian aging 3 people · 0 labs
54. Sleep & longevity 2 people · 0 labs
55. Exercise physiology & aging 11 people · 1 labs
56. Protein intake & anabolic resistance 1 people · 0 labs
57. Multi-omics longitudinal cohorts 4 people · 7 labs
58. Biomarkers & surrogate endpoints 1 people · 1 labs
59. TAME-like trial design 1 people · 1 labs
60. Composite healthspan endpoints 1 people · 1 labs
61. AI target identification 1 people · 2 labs
62. AI generative chemistry 0 people · 1 labs
63. AI aging clocks & foundation models 0 people · 1 labs
64. Aging databases & benchmarks 3 people · 3 labs
65. Organoids & aging models 1 people · 0 labs
66. Mouse lemur, killifish & dog aging models 6 people · 5 labs
67. Gene therapy for aging 1 people · 3 labs
68. Cell therapy for aging 2 people · 3 labs
69. Cryonics & biostasis 1 people · 1 labs
70. Ischemia–reperfusion & resuscitation 3 people · 1 labs
71. Rapamycin in companion animals 2 people · 1 labs
72. Reproductive longevity & menopause 1 people · 0 labs
73. Healthspan economics 1 people · 0 labs
74. Longevity policy (Hevolution, NIA) 16 people · 4 labs
75. Capital formation & longevity VC 17 people · 2 labs
76. Clinical longevity-medicine practice 8 people · 1 labs
77. Diagnostics & consumer clocks 1 people · 0 labs
78. Supplements & evidence grading 5 people · 2 labs
79. Hormesis & xenohormesis 1 people · 1 labs
80. Oxidative-stress reappraisal 8 people · 2 labs
81. Hyperfunction theory 0 people · 1 labs
82. Programmed vs damage theories 2 people · 1 labs
83. Hallmarks & pillars mapping 4 people · 1 labs
84. Single-cell atlas of aging 0 people · 2 labs