Genomics of Ageing and Rejuvenation Lab (University of Birmingham)
Academic
About
The Genomics of Ageing and Rejuvenation Lab, led by João Pedro de Magalhães at the University of Birmingham, studies the genetic, cellular and molecular mechanisms of ageing. Its work centres on experimental and computational methods that bridge genotype and phenotype, with the long-term aim of informing interventions that preserve health by manipulating ageing, including cellular rejuvenation. The lab develops and maintains the Human Ageing Genomic Resources (HAGR), a widely used collection of open databases and tools for ageing research: GenAge (ageing-related genes), AnAge (ageing and life-history data for over 4,000 species), DrugAge (ageing-related drugs in model organisms), GenDR (dietary-restriction genes), LongevityMap (human longevity variants) and CellAge (senescence-associated genes).
Rating breakdown
Aggregate 47/100 · rank #18 in the academic & non-profit table full ratings →
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Publications56
- João Pedro de Magalhães — h-index 82 source ↗
- Human Ageing Genomic Resources: updates on key databases in ageing research (Nucleic Acids Research) ↗
- A multidimensional systems biology analysis of cellular senescence in aging and disease (CellAge; Avelar et al., Genome Biology, 2020) ↗
- The DrugAge database of aging-related drugs (Barardo et al., Aging Cell, 2017) ↗
Discovery100
Trials from ClinicalTrials.gov (this org as lead sponsor), matched to aging by their condition or intervention.
Fundraising0
No public financial records found.
Education10
- João Pedro de Magalhães public communicator
Key outputs
- dataset or tool Human Ageing Genomic Resources (HAGR) ↗
- dataset or tool GenAge database of ageing-related genes ↗
- dataset or tool AnAge database of animal ageing and longevity ↗
- dataset or tool DrugAge database of ageing-related drugs ↗
- dataset or tool GenDR database of dietary-restriction-associated genes ↗
- dataset or tool LongevityMap database of human longevity genetic variants ↗
- dataset or tool CellAge database of cellular senescence genes ↗
- dataset or tool Digital Ageing Atlas: portal of age-related changes across molecular, physiological and pathological levels ↗
- publication Human Ageing Genomic Resources: updates on key databases in ageing research (Nucleic Acids Research) ↗ 2023
- publication A multidimensional systems biology analysis of cellular senescence in aging and disease (CellAge; Avelar et al., Genome Biology, 2020) ↗ 2020
- publication The DrugAge database of aging-related drugs (Barardo et al., Aging Cell, 2017) ↗ 2017
Investment & funding
No grant figure verified in this pass (UKRI/Wellcome records not checked); no amount recorded.