Michael Conboy

Impact

Michael Conboy is a research scientist and lecturer in the Department of Bioengineering at UC Berkeley, where he works in the Conboy laboratory on stem-cell ageing and systemic regulation of tissue repair. He was a co-author of the 2005 Nature heterochronic parabiosis study showing that exposure to a young circulation restored regenerative capacity in aged mouse muscle and liver progenitor cells. As first author with Thomas Rando, he reported non-random template DNA strand segregation and asymmetric fate determination in dividing muscle stem cells (PLoS Biology, 2007). He co-authored the lab's later work on diluting old plasma with saline-albumin in mice (Aging, 2020) and a clinical study of plasma dilution and biological-age markers in humans (GeroScience, 2022). His 2026 papers, all with a UC Berkeley Bioengineering and QB3 affiliation, cover plasma dilution after cardiac ischaemia-reperfusion injury, human aging-on-a-chip models, and metabolic targeting of cancer and senescent cells in old mice.

Metrics

• h-index 32 · google scholar as of 2026-09-23 source ↗

Research output

79 works · 10,347 citations · h-index 31 OpenAlex ↗

Selected publications

• Rejuvenation of aged progenitor cells by exposure to a young systemic environment ↗ 2005 · 2,312 citations
• Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis ↗ 2007 · 1,581 citations
• Notch-Mediated Restoration of Regenerative Potential to Aged Muscle ↗ 2003 · 1,129 citations
• Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair ↗ 2017 · 770 citations
• A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis ↗ 2008 · 688 citations

Links

Research fields